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Rimonabant hydrochloride

In stock
Catalog No.
A3766
CB1 receptor inverse agonist
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
$100.00
In stock
10mg
$91.00
In stock
50mg
$312.00
In stock
100mg
$468.00
In stock

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Background

Rimonabant, also known as SR141716, was the first selective central cannabinoid (CB1) receptor inverse agonist (Ki = 1.8 nM) to be developed as an appetite suppressant, anti-obesity drug. Rimonabant is widely used as a tool to investigate CB receptor properties and the mechanisms by which CB agonists exert their pharmacological effects. In rodent models and clinical trials, rimonabant effectively induces lipolysis, reduces hepatomegaly, decreases body weight, and improves dyslipidemia by reducing triglyceride, free fatty acid, and total cholesterol levels and by increasing HDL/LDL ratios.

Chemical Properties

Physical AppearanceWhite solid
StorageStore at -20°C
M.Wt500.25
Cas No.158681-13-1
FormulaC22H22Cl4N4O
SynonymsSR 141716A; SR 151716A
SolubilitySoluble in DMSO
Chemical Name5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide;hydrochloride
SDFDownload SDF
Canonical SMILESCC1=C(N(N=C1C(=O)NN2CCCCC2)C3=C(C=C(C=C3)Cl)Cl)C4=CC=C(C=C4)Cl.Cl
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

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