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Apoptosis Inducers

Apoptosis, a programmed cell death to eliminate damaged or abnormal cells, is a highly organized physiological process characterized by condensation of nuclear heterochromatin, cell shrinkage and loss of positional organization of organelles in the cytoplasm. Apoptosis inducers are a collection of compounds that are capable of inducing apoptosis in cells. Apoptosis has been extensively studied in numerous researches, where induction of apoptosis has been associated with a variety of events, including activation of p53 gene, transcription factor NF-κB or caspases. Apoptosis inducers have the potential to be incorporated into the management and therapy or prevention of cancer for their ability to induce apoptosis in cancer cells.

  1. Cat.No. Product Name Information
  2. C4403 (±)-Jasmonic Acid methyl ester suppresses proliferation and induces apoptosis
  3. C4698 15-acetoxy Scirpenol mycotoxin that induce apoptotic cell death
  4. A4447 2,3-DCPE hydrochloride Bcl-XL protein expression downregulator
  5. A4188 2-Methoxyestradiol (2-MeOE2) Apoptotic, antiproliferative and antiangiogenic agent
  6. A3118 3,3'-Diindolylmethane Anticancer and antineoplastic agent
  7. C5685 7BIO caspase independent nonapoptotic cell death inducer
  8. A4448 Actinomycin D RNA polymerase inhibitor
  9. A8176 Apicidin Potent HDAC inhibitor
  10. A8188 Atractyloside Dipotassium Salt AAT inhibitor
  11. A3218 BAM7 BAX activator,direct and selective

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