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Mubritinib (TAK 165)

Catalog No.
B1543
Potent inhibitor of HER2/ErbB2
Grouped product items
SizePriceStock Qty
Evaluation Sample
$28.00
In stock
10mg
$50.00
In stock
25mg
$105.00
In stock
200mg
$610.00
In stock

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Email: [email protected]

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Background

Mubritinib (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM; no activity to EGFR, FGFR, PDGFR, JAK1, Src and Blk.

Chemical Properties

StorageStore at -20°C
M.Wt468.47
Cas No.366017-09-6
FormulaC25H23F3N4O2
Solubility≥76.9mg/mL in DMSO with gentle warming
Chemical Name4-[[4-[4-(triazol-1-yl)butyl]phenoxy]methyl]-2-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,3-oxazole
SDFDownload SDF
Canonical SMILESC1=CC(=CC=C1CCCCN2C=CN=N2)OCC3=COC(=N3)C=CC4=CC=C(C=C4)C(F)(F)F
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37°C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.

Quality Control