FGF-21, murine recombinant
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Fibroblast growth factor 21 (FGF-21) is a member of the FGF family that contains more than 20 small (~17–26 kDa) secreted peptides. FGF-21 is mainly secreted by the liver and can travel through the circulatory system and function as an endocrine hormone. FGFs modulate cellular activity via 5 distinct subfamilies of high-affinity FGF receptors (FGFRs): FGFR-1, -2, -3, -4 and -5. FGFRs play an important role in the regulation of glucose and lipid homeostasis. FGF-21 is a potent activator of glucose uptake on adipocytes, protects animals from diet-induced obesity, and lowers blood glucose and triglyceride levels in diabetic rodents.
Mouse FGF-21 is a 210 amino acid (aa) polypeptide that contains a 120 aa core FGF domain and a hydrophobic N-terminus signal sequence that is cleaved to release the soluble 180 aa mature FGF-21 protein. Recombinant mouse FGF-21 produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 183 amino acids including N-terminal Methionine. The amino acid sequence of the recombinant mouse FGF-21 is 100% homologous to the amino acid sequence of the mouse FGF-21 without signal sequence. The FGF-21 is purified by proprietary chromatographic techniques.
Quality Control & DataSheet
- View current batch:
Purity: ≥95%, by SDS-PAGE and HPLC.
Related Biological Data
Related Biological Data
|Gene ID:||56636||Accession #:||Q9JJN1|
|Alternate Names:||mouse FGF-21, FGF-21, FGF21, FGF 21, m-FGF-21, rm-FGF-21, recombinant mouse FGF-21, recombinant FGF-21, FGF.|
|Source:||Escherichia Coli.||M.Wt:||20.1 kDa|
|Appearance:||Lyophilized protein||Storage:||Store at -20°C|
|Formulation:||Lyophilized from filtered (0.4 mm) solution containing 20 mM Tris, pH 7.4 and 20 mM NaCl.|
|Solubility:||Reconstitute in sterile H2O to a concentration ≥ 100 µg/ml. This solution can then be diluted into other aqueous buffers and stored at 4℃ for 1 week or -20℃ for future use.|
|Shipping Condition:||gel pack.||Handling:||Centrifuge the vial prior to opening.|
|Usage:||For Research Use Only! Not to be used in humans.|