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EGTA

Catalog No.
B7195
Calcium chelator
Grouped product items
SizePriceStock Qty
1g
$49.00
In stock

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Email: [email protected]

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Background

EGTA, also known as egtazic acid, is an aminopolycarboxylic acid, a calcium chelator. It can protects against cell death caused by nitric oxide-induced calcium influx into nerve cells[1,2]. 

References:

[1]. Boullerne A I, Nedelkoska L, Benjamins J A. Role of calcium in nitric oxide-induced cytotoxicity: EGTA protects mouse oligodendrocytes. Journal of Neuroscience Research, 2001, 63(2): 124-135.

[2].  Fisher A E O, Hague T A, Clarke C L, et al. Catalytic superoxide scavenging by metal complexes of the calcium chelator EGTA and contrast agent EHPG. Biochemical and Biophysical Research Communications, 2004, 323(1): 0-167.

Product Citation

Chemical Properties

Physical AppearanceA solid
StorageStore at RT
M.Wt380.35
Cas No.67-42-5
FormulaC14H24N2O10
Solubilityinsoluble in DMSO, Limited solubility in EtOH or H2O
Chemical Name3,12-bis(carboxymethyl)-6,9-dioxa-3,12-diazatetradecane-1,14-dioic acid
SDFDownload SDF
Canonical SMILESOC(CN(CC(O)=O)CCOCCOCCN(CC(O)=O)CC(O)=O)=O
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.

Quality Control

Chemical structure

EGTA

Related Biological Data

EGTA