Cyclic di-GMP
Catalog No.
B7839
second messenger
Featured Products
Cyclic di-GMP (CAS 61093-23-0) is an intracellular second messenger involved in diverse bacterial physiological processes, including biofilm formation, motility, and pathogenicity. It functions in mammalian cells as an agonist for Stimulator of Interferon Genes (STING), directly binding and activating it to induce innate immune responses. Due to this mechanism, cyclic di-GMP serves as a valuable tool for investigating STING-mediated immune modulation pathways and has research applications in cancer immunotherapy studies, notably enhancing antitumor immunity in metastatic melanoma models.
| Physical Appearance | A crystalline solid |
| Storage | Store at -20°C |
| M.Wt | 690.41 |
| Cas No. | 61093-23-0 |
| Formula | C20H24N10O14P2 |
| Solubility | insoluble in DMSO; insoluble in EtOH; ≥20.85 mg/mL in H2O |
| Chemical Name | 9,9'-((2R,3R,3aS,7aR,9R,10R,10aS,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidodecahydrodifuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl)bis(2-amino-1H-purin-6(9H)-one) |
| SDF | Download SDF |
| Canonical SMILES | O=C1NC(N)=NC2=C1N=CN2[C@H](O[C@@]([C@@]3([H])OP(O)(OC[C@]([C@@]4([H])OP5(O)=O)(O[C@@H](N6C(N=C(N)NC7=O)=C7N=C6)[C@@H]4O)[H])=O)(CO5)[H])[C@@H]3O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
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Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
- Datasheet
Chemical structure
