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BIIB021

selective and competitive Hsp90 inhibitor

BIIB021

Catalog No. A4058
Size Price Stock Qty
5mg $75.00 In stock
10mg $130.00 In stock
50mg $470.00 In stock
100mg $770.00 In stock

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Sample solution is provided at 25 µL, 10mM.

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Chemical structure

BIIB021

Biological Activity

Description BIIB021 is a selective and competitive inhibitor of Hsp90 with Ki value of 1.7 nM.
Targets Hsp90          
IC50 1.7 nM (Ki)          

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Chemical Properties

Cas No. 848695-25-0 SDF Download SDF
Chemical Name 6-chloro-9-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]purin-2-amine
Canonical SMILES CC1=CN=C(C(=C1OC)C)CN2C=NC3=C2N=C(N=C3Cl)N
Formula C14H15ClN6O M.Wt 318.8
Solubility Soluble in DMSO Storage Store at -20°C
Shipping Condition: Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

Background

BIIB021 is an oral fully synthetic Hsp90 inhibitor that selectively and potently inhibits the molecular chaperone Hsp90 thereby inhibiting the proper assembly of multiple oncogenic proteins involved in tumor growth and survival.