| β-Interleukin I (163-171), human T cell activator |
Sample solution is provided at 25 µL, 10mM.
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Quality Control & MSDS
- View current batch:
-
Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
- Datasheet
Chemical structure
β-Interleukin I (163-171), human Dilution Calculator
β-Interleukin I (163-171), human Molarity Calculator
| Cas No. | 106021-96-9 | SDF | Download SDF |
| Synonyms | H2N-Val-Gln-Gly-Glu-Glu-Ser-Asn-Asp-Lys-OH | ||
| Chemical Name | β-Interleukin I (163-171), human | ||
| Canonical SMILES | CC(C)C(C(=O)NC(CCC(=O)N)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)NC(CC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)O)N | ||
| Formula | C39H64N12O19 | M.Wt | 1004.99 |
| Solubility | >100.4mg/mL in DMSO | Storage | Store at -20°C |
| Shipping Condition | Evaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. | ||
β-Interleukin I (163-171), human(C39H64N12O19), a peptide with the sequence Val-Gln-Gly-Glu-Glu-Ser-Asn-Asp-Lys, MW= 1005. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blood cells (leukocytes). Interleukin 1 alpha and interleukin 1 beta (IL-1 alpha and IL-1 beta) are cytokines that participate in the regulation of immune responses, inflammatory reactions, and hematopoiesis.
Interleukin-1 beta (IL-1β) also known as catabolin, is a cytokine protein that in humans is encoded by the IL1B gene. IL-1β precursor is cleaved by caspase 1 (interleukin 1 beta convertase). Cytosolic thiol protease cleaves the product to form mature IL-1β. IL-1β is a member of the interleukin 1 cytokine family. This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis.
Figure1 Formula of b-Interleukin I (163-171), human
Figure2 Structure of b-Interleukin I
Ref:
1. Contassot E, Beer HD, French LE (2012). "Interleukin-1, inflammasomes, autoinflammation and the skin". Swiss Med Wkly 142: w13590
2. Matzinger P (2012). "The evolution of the danget theory. Interview by Lauren Constable, Commissioning Editor". Expert Rev Clin Immunol 8 (4): 311-7.
3. Sahoo M, Ceballos-Olvera I, del Barrio L, Re F (2011). "Role of the inflammasome, IL-1β, and IL-18 inbacterial infections". ScientificWorldJournal 11: 2037-50.