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7-Ethyl-10-hydroxycamptothecin

Catalog No.
N2133
TOPO I inhibitor
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
$85.00
In stock
20mg
$35.00
In stock

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Email: [email protected]

Worldwide Distributors

Background

Extracted from Camptotheca acuminata Decne. fruit, leaf, branch;Store the product in sealed, cool and dry condition

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt392.4
Cas No.86639-52-3
FormulaC22H20N2O5
Solubility≥11.15mg/mL in DMSO
SDFDownload SDF
Canonical SMILESCCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)O
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Biological Activity

Description 7-Ethyl-10-hydroxycamptothecin is an inhibitor of DNA topoisomerase I with IC50 value of 77 nM.
Targets DNA topoisomerase I          
IC50 77 nM          

Quality Control

Chemical structure

7-Ethyl-10-hydroxycamptothecin