Urolithin A
Catalog No.
B7945
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Urolithin A (CAS 1143-70-0) is a gut microbiota-derived metabolite present naturally in certain foods. It promotes mitochondrial quality by activating mitophagy, the selective degradation of defective mitochondria, thereby supporting mitochondrial biogenesis and cellular respiratory function. Additionally, urolithin A exerts anti-inflammatory and antioxidant effects. In murine CD4? T cells, urolithin A treatment reduces store-operated calcium entry and downregulates STIM1/2 and Orai1 via increased miR-10a-5p expression. Clinical studies suggest oral administration safely modulates skeletal muscle mitochondrial gene expression, highlighting its therapeutic promise for aging research.
| Storage | Store at -20°C |
| M.Wt | 228.20 |
| Cas No. | 1143-70-0 |
| Formula | C13H8O4 |
| Solubility | ≥22.8 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O |
| Chemical Name | 3,8-dihydroxy-6H-benzo[c]chromen-6-one |
| SDF | Download SDF |
| Canonical SMILES | Oc(cc1)cc2c1-c(ccc(O)c1)c1OC2=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
