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TGF-βR1(ALK5)

TGF-βR1 (transforming growth factor beta receptors) are a serine/threonine protein kinase that involved in the regulation of cell cycle arrest, cell proliferation and differentiation, production of extracellular matrix, wound healing, tumorgenesis and immunosuppression etc.

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  1. SD-208
    A3808 SD-208
    Summary: TGF-βR I kinase inhibitor
      Soluble in DMSO
  2. SB-505124 hydrochloride
    A3799 SB-505124 hydrochloride
    Target: ALK
    Summary: ALK5/ALK4/ALK7 inhibitor in TGF-β/activin signalling,selective
      ≥9.3 mg/mL
      insoluble in H2O
  3. A 83-01
    A3133 A 83-01
    Summary: ALK-5 inhibitor
      ≥21.1 mg/mL
      insoluble in H2O
  4. A 77-01
    A3132 A 77-01
    Summary: Potent ALK5 inhibitor
      ≥14.3 mg/mL
      insoluble in H2O

Items 11-14 of 14

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Relate Categories
Category
  • Bcr-Abl 17items
  • PKC 50items
  • Pyk2 3items
  • ROCK 16items
  • SMAD 6items
  • TAK1 1item
  • TGF-βR1(ALK5) 14items
Specificity
  1. Selective 9 items
Target
  1. BMP and Other Activin Receptors 2 items
  2. ALK 2 items
Reported Experiments
  1. Animal Experiments 9 items
  2. Cell Experiments 4 items
Related Disease
  1. Cancer 6 items
  2. Colon Cancer 1 item
  3. Glioblastoma 2 items
  4. Lung Cancer 2 items
  5. Pancreatic Cancer 1 item
  6. Pulmonary Arterial Hypertension 1 item