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PDE

PDE (phosphodiesterases) catalyze the hydrolysis of cGMP and/or cAMP. Stimulus such as light, neurotransmitter and hormone trigger PDE to regulate various biological response including vascular smooth muscle proliferation/contraction, hormone secretion and plate aggregation etc.

Items 21-30 of 55

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  1. Mesopram
    B7257 Mesopram
    Summary: PDE4 inhibitor, orally active
      <26.53 mg/mL
  2. CDP 840 hydrochloride
    B7539 CDP 840 hydrochloride
    Summary: PDE4 inhibitor,potent and selective
      <40.99 mg/mL
  3. Gisadenafil besylate
    B7599 Gisadenafil besylate
    Summary: PDE5 inhibitor
      <6.78 mg/mL
  4. BC 11-38
    B7673 BC 11-38
    Summary: Selective PDE11 inhibitor
      Soluble in DMSO
  5. Milrinone
    B1386 Milrinone
    Target: Phosphodiesterases (PDEs)
    Summary: PDE-3 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥8.2 mg/mL
  6. T 0156 hydrochloride
    B5162 T 0156 hydrochloride
    Summary: inhibitor of phosphodiesterase type 5 (PDE5)
      <14.59 mg/mL
  7. Apremilast (CC-10004)
    A4317 Apremilast (CC-10004)
    Target: Phosphodiesterases (PDEs)
    Summary: PDE4 inhibitor
      ≥23.05 mg/mL
  8. Roflumilast
    A4319 Roflumilast
    Summary: PDE-4 inhibitor
      insoluble in H2O; ≥20.2 mg/mL
  9. Sildenafil Citrate
    A4321 Sildenafil Citrate
    Target: Phosphodiesterases (PDEs)
    Summary: Treat erectile dysfunction and PAH
      ≥25.35 mg/mL
  10. Vardenafil HCl Trihydrate
    A4323 Vardenafil HCl Trihydrate
    Target: Phosphodiesterases (PDEs)
    Summary: PDE5 inhibitor, potent and selective
      ≥13.3 mg/mL

Items 21-30 of 55

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