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PDE

PDE (phosphodiesterases) catalyze the hydrolysis of cGMP and/or cAMP. Stimulus such as light, neurotransmitter and hormone trigger PDE to regulate various biological response including vascular smooth muscle proliferation/contraction, hormone secretion and plate aggregation etc.

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  1. CDP 840 hydrochloride
    B7539 CDP 840 hydrochloride
    Summary: PDE4 inhibitor,potent and selective
      <40.99 mg/mL
  2. Gisadenafil besylate
    B7599 Gisadenafil besylate
    Summary: PDE5 inhibitor
      <6.78 mg/mL
  3. BC 11-38
    B7673 BC 11-38
    Summary: Selective PDE11 inhibitor
      Soluble in DMSO
  4. Milrinone
    B1386 Milrinone
    Target: Phosphodiesterases (PDEs)
    Summary: PDE-3 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥8.2 mg/mL
  5. Pimobendan hydrochloride
    B1165 Pimobendan hydrochloride
    Summary: Selective inhibitor of PDE3
      Soluble in DMSO
  6. MY-5445
    B6301 MY-5445
    Summary: PDE5 inhibitor
      Soluble in DMSO
  7. Etazolate hydrochloride
    B6304 Etazolate hydrochloride
     2 Citation
    Target: Phosphodiesterases (PDEs)
    Summary: PDE-4 inhibitor and selective GABA-A receptor modulator
      ≥7.75 mg/mL
  8. Vinpocetine
    B2276 Vinpocetine
    Target: Phosphodiesterases (PDEs)
    Summary: PDE inhibitor
      ≥2.59 mg/mL
  9. Apremilast (CC-10004)
    A4317 Apremilast (CC-10004)
    Target: Phosphodiesterases (PDEs)
    Summary: PDE4 inhibitor
      ≥23.05 mg/mL
  10. Roflumilast
    A4319 Roflumilast
    Summary: PDE-4 inhibitor
      insoluble in H2O; ≥20.2 mg/mL

Items 21-30 of 55

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