Toggle Nav
mobile icon
My Cart
Close
  • Menu
  • Setting

PDE

PDE (phosphodiesterases) catalyze the hydrolysis of cGMP and/or cAMP. Stimulus such as light, neurotransmitter and hormone trigger PDE to regulate various biological response including vascular smooth muscle proliferation/contraction, hormone secretion and plate aggregation etc.

Items 31-40 of 55

Page
per page
  1. PF-2545920
    A4325 PF-2545920
    Target: Phosphodiesterases (PDEs)
    Summary: PDE10A inhibitor,potent and selective
      insoluble in H2O; ≥19.35 mg/mL
  2. Tadalafil
    A4327 Tadalafil
    Target: Phosphodiesterases (PDEs)
    Summary: PDE5 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥16.6 mg/mL
  3. Rolipram
    A4328 Rolipram
    Target: Phosphodiesterases (PDEs)
    Summary: PDE4-inhibitor and an anti-inflammatory agent
      insoluble in H2O; ≥13 mg/mL
  4. Cilomilast
    A4329 Cilomilast
    Target: Phosphodiesterases (PDEs)
    Summary: Potent PDE4 inhibitor
      insoluble in H2O; ≥12.95 mg/mL
  5. GSK256066
    A4331 GSK256066
    Summary: PDE4-inhibitor, selective and highly potent
      insoluble in DMSO; insoluble in EtOH; insoluble in H2O
  6. Avanafil
    A4334 Avanafil
    Target: Phosphodiesterases (PDEs)
    Summary: PDE5 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥17.6 mg/mL
  7. Cilostazol
    A4337 Cilostazol
    Summary: PDE3 inhibitor
      insoluble in H2O; ≥15.4 mg/mL
  8. Pimobendan
    A4340 Pimobendan
    Target: Phosphodiesterases (PDEs)
    Summary: Selective PDE3 inhibitor.Ca2+ channel sensitizer
      insoluble in H2O; ≥16.2 mg/mL
  9. Dyphylline
    A4343 Dyphylline
    Summary: Pan-PDE inhibitor
      ≥17.17 mg/mL
  10. Aminophylline
    A4346 Aminophylline
    Target: Phosphodiesterases (PDEs)
    Summary: Pan-PDE inhibitor
      ≥13.48 mg/mL

Items 31-40 of 55

Page
per page