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EGFR

EGFR (epidermal growth factor receptor) is the cell-surface receptor of its specific ligands, including epidermal growth factor and TGFα (transforming growth factor α) and is a receptor tyrosine kinase.

Items 31-40 of 41

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  1. AZD-9291 mesylate
    B1105 AZD-9291 mesylate
    Summary: third generation EGFRm inhibitor, oral and irreversible
      insoluble in EtOH; insoluble in DMSO; insoluble in H2O
  2. RG 13022
    B6115 RG 13022
    Summary: EGFR tyrosine kinase inhibitor
      ≥26.6 mg/mL
  3. Compound 56
    A8197 Compound 56
     1 Citation
    Target: EGFR
    Summary: REGFR inhibitor
      insoluble in H2O; ≥16.95 mg/mL
  4. PD153035 hydrochloride
    A8199 PD153035 hydrochloride
     1 Citation
    Target: EGFR
    Summary: Potent EGFR inhibitor
      insoluble in EtOH; insoluble in H2O; ≥3.97 mg/mL
  5. CUDC-101
    A4092 CUDC-101
     1 Citation
    Target: Histone Deacetylases (HDACs)|EGFR|ErbB
    Summary: Multitargeted HDAC inhibitor
      ≥21.7 mg/mL
  6. AG-490
    A4139 AG-490
     3 Citation
    Target: EGFR|JAK
    Summary: JAK2/EGFR inhibitor
      insoluble in H2O; ≥14.7 mg/mL
  7. BMS-690514
    A3256 BMS-690514
    Summary: HER/EGFR inhibitor
      Soluble in DMSO
  8. CO-1686 (AVL-301)
    A3320 CO-1686 (AVL-301)
     1 Citation
    Target: EGFR
    Summary: EGFR inhibitor
      ≥27.8 mg/mL
  9. Erlotinib
    A3397 Erlotinib
     4 Citation
    Summary: EGFR tyrosine kinase inhibitor
      insoluble in H2O; ≥19.65 mg/mL
  10. Gefitinib hydrochloride
    A3433 Gefitinib hydrochloride
    Target: EGFR
    Summary: Potent EGFR inhibitor
      insoluble in EtOH; ≥4.28 mg/mL

Items 31-40 of 41

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