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EGFR

EGFR (epidermal growth factor receptor) is the cell-surface receptor of its specific ligands, including epidermal growth factor and TGFα (transforming growth factor α) and is a receptor tyrosine kinase.

Items 21-30 of 41

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  1. ARRY-380
    A8366 ARRY-380
    Target: HER2
    Summary: Tyrosine kinase HER2 and p95-HER2 inhibitor
      ≥28.5 mg/mL
  2. AST-1306
    A8367 AST-1306
    Summary: EGFR/HER2 inhibitor
      ≥22.45 mg/mL
  3. AZD8931 (Sapitinib)
    A8375 AZD8931 (Sapitinib)
    Target: EGFR|ErbB
    Summary: ErbB inhibitor
      ≥23.7 mg/mL
  4. OSI-420 free base
    B1495 OSI-420 free base
    Summary: EGFR inhibitor
      insoluble in H2O; insoluble in EtOH; ≥51 mg/mL
  5. AST-1306 TsOH
    B1020 AST-1306 TsOH
    Summary: ErbB2 and EGFR inhibitor
      Soluble in DMSO
  6. AZ5104
    B5836 AZ5104
    Target: EGFR
    Summary: EGFR inhibitor
      insoluble in H2O; ≥16.95 mg/mL
  7. AZD3759
    B5962 AZD3759
    Summary: EGFR inhibitor，oral active
      ≥23 mg/mL
  8. AZD-9291
    B1104 AZD-9291
     1 Citation
    Target: EGFR
    Summary: Mutated forms EGFR inhibitor
      ≥24.98 mg/mL
  9. AZD-9291 mesylate
    B1105 AZD-9291 mesylate
    Summary: third generation EGFRm inhibitor, oral and irreversible
      insoluble in EtOH; insoluble in DMSO; insoluble in H2O
  10. Mutant EGFR inhibitor
    B1103 Mutant EGFR inhibitor
    Summary: Selective Mutated EGFR inhibitor
      Soluble in DMSO

Items 21-30 of 41

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