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Cyclin-Dependent Kinases

Cyclin-dependent kinases is a group of serine/threonine kinases. It is activated by binding to cyclin and participates in the regulation of cell cycle.

Items 11-18 of 18

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  1. AT7519
    A5719 AT7519
    Target: Cyclin-Dependent Kinases
    Summary: Multi-CDK inhibitor
  2. PD 0332991 (Palbociclib) HCl
    A8316 PD 0332991 (Palbociclib) HCl
     5 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor,highly selective
      ≥14.48 mg/mL
  3. AZD-5438
    A8326 AZD-5438
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Potent CDK1/2/9 inhibitor
      insoluble in H2O; ≥18.55 mg/mL
  4. PHA-848125
    A8501 PHA-848125
    Target: Cyclin-Dependent Kinases
    Summary: CDK inhibitor,potent and ATP-competitive
      ≥23.05 mg/mL
  5. Dinaciclib (SCH727965)
    A8412 Dinaciclib (SCH727965)
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Potent CDK inhibitor
  6. Purvalanol B
    A8565 Purvalanol B
     1 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK1/CDK2/CDK4 inhibitor
      ≥21.65 mg/mL
  7. R547
    A8642 R547
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK1/2/4 inhibitor,ATP-competitive
      Soluble in DMSO
  8. AMG 925
    B3277 AMG 925
    Target: Cyclin-Dependent Kinases|FLT3
    Summary: FLT3/CDK4 inhibitor,potent and selective
      insoluble in DMSO; insoluble in H2O; insoluble in EtOH

Items 11-18 of 18

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