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Cyclin-Dependent Kinases

Cyclin-dependent kinases is a group of serine/threonine kinases. It is activated by binding to cyclin and participates in the regulation of cell cycle.

Items 11-20 of 65

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  1. Palbociclib (PD0332991) Isethionate
    A8335 Palbociclib (PD0332991) Isethionate
     1 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor,highly selective
      ≥28.7 mg/mL
  2. PHA-848125
    A8501 PHA-848125
    Target: Cyclin-Dependent Kinases
    Summary: CDK inhibitor,potent and ATP-competitive
      ≥23.05 mg/mL
  3. BMS265246
    A8385 BMS265246
    Target: Cyclin-Dependent Kinases
    Summary: CDK1/2 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; ≥17.25 mg/mL
  4. Dinaciclib (SCH727965)
    A8412 Dinaciclib (SCH727965)
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Potent CDK inhibitor
  5. Purvalanol B
    A8565 Purvalanol B
     1 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK1/CDK2/CDK4 inhibitor
      ≥21.65 mg/mL
  6. Deferasirox
    A8639 Deferasirox
    Summary: Oral iron chelator
      insoluble in H2O; ≥37.28 mg/mL
  7. Flavopiridol hydrochloride
    A8640 Flavopiridol hydrochloride
    Summary: CDK inhibitor, potent and selective
      ≥21.9 mg/mL
  8. LEE011
    A8641 LEE011
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥10.88 mg/mL
  9. R547
    A8642 R547
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK1/2/4 inhibitor,ATP-competitive
      Soluble in DMSO
  10. WHI-P180
    A8643 WHI-P180
    Summary: EGFR/Janus Kinase 3 inhibitor
      Soluble in DMSO

Items 11-20 of 65

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