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Signaling Pathways

Signaling Pathways

A4182 Resveratrol
2 Citation

Target: Sir2-like Family Deacetylases (Sirtuins)|COX|LOX|Adenylyl cyclase|Quinone reductase

Summary: SIRT1 activator
A4038 Alogliptin (SYR-322)
1 Citation

Target: DPP-4

Summary: DPP-4 inhibitor,potent and highly selective
A4011 ONX-0914 (PR-957)
6 Citation

Target: Proteasome

Summary: Immunoproteasome inhibitor,potent and selective

≥29.03 mg/mL
A4364 Methazolamide

Target: Carbonic Anhydrases

Summary: Carbonic anhydrase inhibitor
A3723 Phloretin

Target: SGLT

Summary: A dihydrochalcone found in apple

insoluble in H2O; ≥105 mg/mL
A3865 Teneligliptin hydrobromide

Target: DPP-4

Summary: Dipeptidyl peptidase-4 inhibitor

≥62.9 mg/mL
A3893 Troglitazone

Target: PPAR

Summary: Selective PPARγ agonist

insoluble in H2O; ≥20.9 mg/mL
B1296 Glibenclamide

Target: Inward Rectifier Potassium (Kir) Channels

Summary: Insulin production modulator

≥49.4 mg/mL
B1879 AdipoRon

Target: AdipoR1|AdipoR2

Summary: AdipoR1 and AdipoR2 agonist, first orally active

≥21.45 mg/mL
A8395 CHIR-98014

Target: GSK-3

Summary: GSK-3β inhibitor,selective and ATP-competitive

insoluble in H2O; insoluble in EtOH; ≥8.1 mg/mL