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GlibenclamideInsulin production modulator

Glibenclamide

Catalog No. B1296
Size Price Stock Qty
10mM (in 1mL DMSO) $50.00 In stock
500mg $48.00 In stock
1g $66.00 In stock

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Sample solution is provided at 25 µL, 10mM.

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Chemical structure

Glibenclamide

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Chemical Properties

Cas No. 10238-21-8 SDF Download SDF
Chemical Name 5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
Canonical SMILES COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
Formula C23H28ClN3O5S M.Wt 494
Solubility Soluble in DMSO Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

Background

Glibenclamide is a sulfonylurea compound that modulates insulin production. Sulfonylureas bind to ATP-dependent K+ channels in beta cells of the pancreas, depolarizing them and stimulating the release of Ca2+, which in turn stimulates insulin production.