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Signaling Pathways

Items 11-20 of 51

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  1. Q-VD-OPh
    A1901 Q-VD-OPh
     53 Citation
    Target: Caspases
    Summary: Cell-permeable, irreversible pan-caspase inhibitor
      ≥25.67 mg/mL
  2. Z-DEVD-FMK
    A1920 Z-DEVD-FMK
     12 Citation
    Target: Caspases
    Summary: Caspase-3 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥60 mg/mL
  3. Z-DQMD-FMK
    A1921 Z-DQMD-FMK
     3 Citation
    Target: Caspases
    Summary: Caspase-3 inhibitor,cell-permeable
      ≥29.2 mg/mL
  4. Z-VEID-FMK
    A1923 Z-VEID-FMK
     2 Citation
    Target: Caspases
    Summary: Caspase-6 inhibitor
      insoluble in H2O; ≥113.4 mg/mL
  5. Caspase-3/7 Inhibitor I
    A1925 Caspase-3/7 Inhibitor I
     2 Citation
    Target: Caspases
    Summary: Caspase-3/7 inhibitor
      insoluble in H2O; ≥16.2 mg/mL
  6. Q-VD(OMe)-OPh
    A8165 Q-VD(OMe)-OPh
     6 Citation
    Target: Caspases
    Summary: Pan-caspase inhibitor
      ≥26.35 mg/mL
  7. Bardoxolone
    A3220 Bardoxolone
    Target: COX|iNOS
    Summary: Once-a-day treatment for CKD
      ≥49.2 mg/mL
  8. Nonivamide (Capsaicin Analog)
    A3278 Nonivamide (Capsaicin Analog)
     1 Citation
    Target: TRP Channel
    Summary: TRPV1 receptor agonist
      insoluble in H2O; ≥15.27 mg/mL
  9. D609
    A3343 D609
    Target: PC-PLC
    Summary: PC-PLC inhibitor
      ≥12.7 mg/mL
  10. LCL161
    A3541 LCL161
     1 Citation
    Target: Inhibitor of apoptosis proteins (IAP)
    Summary: Antagonist of IAPs inhibitor
      ≥25.05 mg/mL

Items 11-20 of 51

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Category
  1. Caspase11item
  2. Apoptosis Inducers8item
  3. Bcl-2 Family14item
  4. Bcl-xL4item
  5. c-RET2item
  6. IAP4item
  7. KEAP1-Nrf22item
  8. MDM21 item
  9. p533item
  10. PC-PLC1 item
  11. PKD1 item
  12. Survivin1 item
  13. Thymidylate Synthase1 item
  14. TNF-α4item
  15. Other Apoptosis1 item
Reversibility
  1. Reversible1 item
  2. Irreversible6item
Target
  1. Caspases11item
  2. Proteasome1 item
  3. Histone Deacetylases (HDACs)1 item
  4. Inhibitor of apoptosis proteins (IAP)3item
  5. Bcl-26item
  6. Raf1 item
  7. Bcl-xl3item
  8. MDM22item
  9. VEGFR2item
  10. PDGFR2item
  11. c-Kit1 item
  12. RET1 item
  13. Mcl-15item
  14. Bcr-Abl1 item
  15. Nrf21 item
  16. Deubiquitinating enzymes (DUBs)1 item
  17. RIP kinases1 item
  18. Survivin1 item
  19. Dehydrogenase1 item
  20. Mixed lineage kinase domain-like protein (MLKL)1 item
  21. COX1 item
  22. iNOS1 item
  23. TRP Channel1 item
  24. Apoptosis Inducers1 item
  25. angiogenesis1 item
  26. p53-MDM2 interaction1 item
  27. PC-PLC1 item
  28. PKD1 item
  29. MCL11 item
  30. Bcl-w1 item
Reported Experiments
  1. Animal Experiments41item
  2. Cell Experiments25item
Related Disease
  1. Acute Myeloid Leukemia1 item
  2. Adrenocortical Carcinoma1 item
  3. Autoimmune Diseases1 item
  4. Breast Cancer9item
  5. Cancer33item
  6. Chronic Lymphocytic Leukemia1 item
  7. Chronic Myeloproliferative Disorders1 item
  8. Colon Cancer4item
  9. Colorectal Cancer3item
  10. Glioblastoma4item
  11. Hepatocellular Carcinoma1 item
  12. Inflammatory Diseases1 item
  13. Lung Cancer3item
  14. Lymphoma4item
  15. Melanoma2item
  16. Multiple Myeloma2item
  17. Myelofibrosis1 item
  18. Myeloma1 item
  19. Neuroblastoma1 item
  20. Non-small Cell Lung Cancer4item
  21. Ovarian Cancer1 item
  22. Pain Relief1 item
  23. Pancreatic Cancer3item
  24. Prostate Cancer5item
  25. Pulmonary Fibrosis1 item
  26. Rheumatoid Arthritis1 item
  27. Soft Tissue Sarcoma1 item
  28. Testicular Cancer1 item