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Signaling Pathways

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  1. KC7F2
    A4507 KC7F2
    Summary: HIF-1α inhibitor
      ≥137.4 mg/mL
  2. PX 12
    A4509 PX 12
    Target: Trx
    Summary: Trx-1 inhibitor
      insoluble in H2O; ≥8.75 mg/mL
  3. DMOG
    A4506 DMOG
    Target: Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs)
    Summary: Competitive HIF-PH inhibitor, cell-permeable
  4. FG2216
    B5851 FG2216
    Target: Pyruvate dehydrogenases (PDH)
    Summary: HIF-prolyl hydroxylase inhibitor
      insoluble in H2O; ≥14.05 mg/mL
  5. Daprodustat(GSK1278863)
    B6106 Daprodustat(GSK1278863)
    Summary: HIF-prolyl hydroxylase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥7.86 mg/mL
  6. Octyl-α-ketoglutarate
    C4321 Octyl-α-ketoglutarate
    Summary: prolyl hydroxylases (PHD) activator
      ≤20 mg/mL
  7. Adaptaquin
    C4377 Adaptaquin
    Summary: HIF-prolyl hydroxylase-2 (PHD2) inhibitor
      ≤30 mg/mL
  8. JNJ-42041935
    C4752 JNJ-42041935
    Summary: Hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) inhibitor
      ≤10 mg/mL
  9. 2,4-DPD
    C4887 2,4-DPD
    Summary: cell permeable, competitive inhibitor of HIF-PH
      ≤50 mg/mL
  10. BAY 87-2243
    B1115 BAY 87-2243
    Target: Hypoxia Inducible Factors (HIFs)
    Summary: HIF-1 inhibitor,potent and selective

Items 1-10 of 13

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