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Signaling Pathways

Signaling Pathways

A4092 CUDC-101
1 Citation

Target: Histone Deacetylases (HDACs)|EGFR|ErbB

Summary: Multitargeted HDAC inhibitor

≥21.7 mg/mL
A4139 AG-490
3 Citation

Target: EGFR|JAK

Summary: JAK2/EGFR inhibitor

insoluble in H2O; ≥14.7 mg/mL
A3320 CO-1686 (AVL-301)
1 Citation

Target: EGFR

Summary: EGFR inhibitor

≥27.8 mg/mL
A3433 Gefitinib hydrochloride

Target: EGFR

Summary: Potent EGFR inhibitor

insoluble in EtOH; ≥4.28 mg/mL
B1104 AZD-9291
1 Citation

Target: EGFR

Summary: Mutated forms EGFR inhibitor

≥24.98 mg/mL
B5836 AZ5104

Target: EGFR

Summary: EGFR inhibitor

insoluble in H2O; ≥16.95 mg/mL
A8319 Dacomitinib (PF299804, PF299)

Target: ErbB

Summary: HER inhibitor

≥23.5 mg/mL
A8357 AG-1478

Target: EGFR

Summary: EGFR inhibitor,potent and selective

insoluble in H2O; ≥15.8 mg/mL
A8366 ARRY-380

Target: HER2

Summary: Tyrosine kinase HER2 and p95-HER2 inhibitor

≥28.5 mg/mL
A8375 AZD8931 (Sapitinib)

Target: EGFR|ErbB

Summary: ErbB inhibitor

≥23.7 mg/mL