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Signaling Pathways

Signaling Pathways

A3962 AZD1208

Target: Pim

Summary: PIM kinase inhibitor

insoluble in EtOH; insoluble in H2O; ≥18.95 mg/mL
A4512 Cucurbitacin I

Target: STAT|JAK

Summary: STAT3/JAK2 signaling inhibitor

≥22.45 mg/mL
A8218 Lapatinib
2 Citation

Target: ErbB

Summary: EGFR/HER2 inhibitor,potent,selective and reversible

≥29.05 mg/mL
A8219 Gefitinib (ZD1839)
3 Citation

Target: EGFR

Summary: Selective EGFR inhibitor

≥22.34 mg/mL
A8247 Afatinib (BIBW2992)
1 Citation

Target: EGFR

Summary: Irreversible EGFR/HER2 inhibitor

≥24.3 mg/mL
A2412 CP-724714

Target: VEGFR|PDGFR|Bcr-Abl|Src|EGFR|c-MET|Insulin Receptors|IRG-1R

Summary: HER2 inhibitor,potent and selective

≥23.5 mg/mL
A1393 WZ8040

Target: EGFR

Summary: EGFR T790M inhibitor,irreversible amd potent

≥24.05 mg/mL
A2822 AC480 (BMS-599626)

Target: EGFR

Summary: HER1/2 inhibitor,selective and efficacious

≥28.35 mg/mL
A5424 Fludarabine

Summary: DNA synthsis inhibitor

insoluble in H2O; insoluble in EtOH; ≥9.25 mg/mL
A2224 Stattic
5 Citation

Target: STAT

Summary: STAT3 inhibitor,small-molecule and potent

insoluble in H2O; insoluble in EtOH; ≥10.56 mg/mL