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Signaling Pathways

Items 21-30 of 71

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  1. Colchicine
    A3324 Colchicine
    Target: Microtubules/Tubulins
    Summary: Tubulin Inhibitor
      ≥19.97 mg/mL
  2. CVT-313
    A3336 CVT-313
     1 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Cdk2 inhibitor
      ≥20 mg/mL
  3. Epothilone D
    A3394 Epothilone D
    Target: Microtubule/Tubulin
    Summary: Natural polyketide compound
      Soluble in DMSO
  4. Flavopiridol
    A3417 Flavopiridol
    Target: Cyclin-Dependent Kinases
    Summary: Pan-cdk inhibitor
      insoluble in H2O; ≥40.2 mg/mL
  5. GSK2606414
    A3448 GSK2606414
     4 Citation
    Summary: PERK inhibitor,potent and selective
      ≥22.57 mg/mL
  6. Hydroxyfasudil
    A3478 Hydroxyfasudil
    Target: ROCK|Rho-kinase
    Summary: Rho-kinase inhibitor and vasodilator
      Soluble in DMSO
  7. PHA-767491
    A3721 PHA-767491
    Target: Cyclin-Dependent Kinases|MK2|Cdc7
    Summary: Cdc7/cdk9 inhibitor, potent, ATP-competitive
      insoluble in H2O; insoluble in EtOH; ≥10.65 mg/mL
  8. Poloxin
    A3732 Poloxin
    Target: PLK
    Summary: PLK1 inhibitor
      insoluble in H2O; ≥14.85 mg/mL
  9. Reversine
    A3760 Reversine
    Target: Aurora Kinases
    Summary: A3 adenosine receptor antagonist,ARK-1/-2/-3 inhibitor
      insoluble in H2O; ≥19.65 mg/mL
  10. RI-1
    A3764 RI-1
    Target: RAD51
    Summary: RAD51 inhibitor,cell-permeable
      insoluble in H2O; ≥18.1 mg/mL

Items 21-30 of 71

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  1. ATM/ATR4item
  2. Aurora Kinase17item
  3. Cdc421 item
  4. Cdc71 item
  5. Chk4item
  6. CRM11 item
  7. Cyclin-Dependent Kinases18item
  8. E1 enzyme1 item
  9. Ksp1 item
  10. Microtubule/Tubulin5item
  11. RAD511 item
  12. ROCK5item
  13. Rho3item
  14. PERK1 item
  15. PLK8item
  16. PTEN1 item
Specificity
  1. Selective39item
Reversibility
  1. Reversible4item
  2. Irreversible1 item
Target
  1. Cyclin-Dependent Kinases20item
  2. PI3K1 item
  3. Aurora Kinases16item
  4. mTOR1 item
  5. FLT35item
  6. GSK-31 item
  7. PLK9item
  8. Chk4item
  9. VEGFR1 item
  10. PDGFR1 item
  11. RET1 item
  12. Bromodomain-containing proteins(BRDs)1 item
  13. MEK1 item
  14. FGFR1 item
  15. Src3item
  16. Microtubules/Tubulins1 item
  17. ROCK5item
  18. JAK1 item
  19. DNA-PK1 item
  20. Ksp1 item
  21. PKC1 item
  22. RAD511 item
  23. LRRK21 item
  24. PKG1 item
  25. PKA1 item
  26. Myosin light chain kinases (MLCKs)1 item
  27. MK21 item
  28. ATM/ATR4item
  29. Farnesyl Diphosphate Synthases1 item
  30. Cdc421 item
  31. Hck1 item
  32. Cdc71 item
  33. Ubiquitin-activating Enzyme E11 item
  34. Microtubule/Tubulin3item
  35. VEGFR3/FLT41 item
  36. NTRK1/TRKA1 item
  37. CSF-1R/c-Fms1 item
  38. nuclear export1 item
  39. CRM11 item
  40. Hec11 item
  41. Histone Acetyltransferases (HATs)1 item
  42. Rho1 item
  43. Lck1 item
  44. FGR1 item
  45. YES1 item
  46. Fyn1 item
  47. ARG1 item
  48. Rho-kinase1 item
  49. PTEN1 item
Related Disease
  1. Acute Myeloid Leukemia3item
  2. B-lymphoid Malignancies1 item
  3. Breast Cancer4item
  4. Cancer48item
  5. Cervical Cancer1 item
  6. Chronic Lymphocytic Leukemia2item
  7. Colon Cancer3item
  8. Colon Carcinoma1 item
  9. Colorectal Cancer3item
  10. Glioma2item
  11. Leukemia1 item
  12. Lung Cancer2item
  13. Lymphoma2item
  14. Mantle Cell Lymphoma1 item
  15. Melanoma1 item
  16. Multiple Myeloma1 item
  17. Ovarian Cancer3item
  18. Pancreatic Cancer4item
  19. Prostate Cancer2item
  20. Renal Cell Carcinoma1 item
  21. Thyroid Cancer1 item