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Signaling Pathways

Items 151-160 of 241

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  1. NVP-BEP800
    A4064 NVP-BEP800
    Target: HSP90
    Summary: Oral Hsp90β inhibitor, novel, fully synthetic
  2. PF-04929113 (SNX-5422)
    A4065 PF-04929113 (SNX-5422)
    Target: HSP90
    Summary: Hsp90 inhibitor,potent and selective
      ≥23.85 mg/mL
  3. Radicicol
    A4067 Radicicol
    Summary: ATPase/kinase inhibitor
      Soluble in ethanol
  4. SNX-2112
    A4068 SNX-2112
     1 Citation
    Summary: Hsp90 inhibitor,ATP-competitve,potent and selective
      ≥23.05 mg/mL
  5. BMS-707035
    A4069 BMS-707035
    Target: HIV Integrases
    Summary: HIV-I integrase inhibitor,potent and specific
      insoluble in EtOH; insoluble in H2O; ≥41 mg/mL
  6. Elvitegravir (GS-9137)
    A4070 Elvitegravir (GS-9137)
    Target: HIV Integrases
    Summary: HIV-1 integrase inhibitor,potent
      insoluble in H2O; insoluble in EtOH; ≥20.35 mg/mL
  7. Fluorouracil (Adrucil)
    A4071 Fluorouracil (Adrucil)
     3 Citation
    Target: Thymidylate Synthase
    Summary: Antitumor agent;inhibitor of thymidylate synthase
      insoluble in EtOH; ≥10.04 mg/mL
  8. MK-2048
    A4072 MK-2048
    Summary: Integrase inhibitor for HIV-1,second generation
      ≥10.55 mg/mL
      insoluble in H2O
  9. Raltegravir (MK-0518)
    A4073 Raltegravir (MK-0518)
     1 Citation
    Target: integrase
    Summary: HIV-1 integrase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥19.95 mg/mL
  10. S/GSK1349572
    A4074 S/GSK1349572
    Summary: HIV integrase inhibitor, novel and potent
      ≥41.9 mg/mL

Items 151-160 of 241

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Category
  1. Caspase25item
  2. Aminopeptidase8item
  3. ACE9item
  4. Calpains11item
  5. Carboxypeptidase4item
  6. Cathepsin12item
  7. DPP-418item
  8. Elastase10item
  9. Gamma Secretase18item
  10. HCV Protease15item
  11. HSP25item
  12. HIV Integrase12item
  13. HIV Protease13item
  14. MMP25item
  15. NS3/4a protease4item
  16. Serine Protease9item
  17. Thrombin14item
  18. Urokinase2item
  19. Other Proteases11item
  20. Tyrosinases1 item
Specificity
  1. Selective80item
  2. Non-Selective1 item
Reversibility
  1. Reversible14item
  2. Irreversible13item
Target
  1. Caspases13item
  2. Proteasome1 item
  3. Cathepsins11item
  4. MMP6item
  5. Factor Xa3item
  6. Thymidylate Synthase1 item
  7. Aminopeptidases3item
  8. HSP9012item
  9. Notch1 item
  10. thrombin1 item
  11. Renin1 item
  12. HIV proteases1 item
  13. Pepsins1 item
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  15. Calpains5item
  16. HCV Proteases3item
  17. Trypsins1 item
  18. Trypsin1 item
  19. Chymotrypsin1 item
  20. Kallikrein1 item
  21. Trypsinogen1 item
  22. HIV-1 gp1201 item
  23. HIV Integrases2item
  24. Urokinases1 item
  25. Inward Rectifier Potassium (Kir) Channels1 item
  26. Papains1 item
  27. DPP-45item
  28. Nonstructural protein 5B (NS5B)1 item
  29. ADAMs1 item
  30. Dipeptidyl-peptidase II1 item
  31. metalloprotease1 item
  32. cysteine protease2item
  33. HCV polymerase2item
  34. Subtilisin/Kex2p-like proprotein convertase1 item
  35. Elastases1 item
  36. integrase1 item
  37. HCV NS3-4A protease1 item
  38. NE1 item
Reported Experiments
  1. Animal Experiments90item
  2. Cell Experiments69item
Related Disease
  1. Acute Lung Injury1 item
  2. Acute Myeloid Leukemia1 item
  3. Breast Cancer11item
  4. Cancer35item
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  17. Melanoma7item
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  19. Neuroblastoma1 item
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  21. Osteoporosis1 item
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