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Serotonin HCl

Catalog No.
B1830
Endogenous 5-HT receptor agonist
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
$60.00
In stock
50mg
$50.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

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Background

Serotonin hydrochloride (CAS 153-98-0) is a monoamine neurotransmitter naturally derived from tryptophan that functions as an endogenous agonist of serotonin (5-HT) receptors. Additionally, serotonin hydrochloride acts as a non-competitive inhibitor of the enzyme catechol O-methyltransferase (COMT), exhibiting a binding affinity (Ki) of approximately 44 μM. Serotonin modulates diverse physiological processes, including mood regulation, sleep, appetite, sexual function, and gastrointestinal activity. Due to its role in mediating neurological and inflammatory pathways, serotonin hydrochloride is widely utilized in research studies investigating depression, anxiety disorders, migraine pathophysiology, and inflammation-associated hypersensitivity.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt212.68
Cas No.153-98-0
FormulaC10H12N2O·HCl
Solubility≥11.12 mg/mL in EtOH with ultrasonic; ≥22.35 mg/mL in H2O; ≥8.2 mg/mL in DMSO
Chemical Name3-(2-aminoethyl)-1H-indol-5-ol;hydrochloride
SDFDownload SDF
Canonical SMILESC1=CC2=C(C=C1O)C(=CN2)CCN.Cl
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

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