Serotonin HCl
Serotonin hydrochloride (CAS 153-98-0) is a monoamine neurotransmitter naturally derived from tryptophan that functions as an endogenous agonist of serotonin (5-HT) receptors. Additionally, serotonin hydrochloride acts as a non-competitive inhibitor of the enzyme catechol O-methyltransferase (COMT), exhibiting a binding affinity (Ki) of approximately 44 μM. Serotonin modulates diverse physiological processes, including mood regulation, sleep, appetite, sexual function, and gastrointestinal activity. Due to its role in mediating neurological and inflammatory pathways, serotonin hydrochloride is widely utilized in research studies investigating depression, anxiety disorders, migraine pathophysiology, and inflammation-associated hypersensitivity.
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 212.68 |
Cas No. | 153-98-0 |
Formula | C10H12N2O·HCl |
Solubility | ≥11.12 mg/mL in EtOH with ultrasonic; ≥22.35 mg/mL in H2O; ≥8.2 mg/mL in DMSO |
Chemical Name | 3-(2-aminoethyl)-1H-indol-5-ol;hydrochloride |
SDF | Download SDF |
Canonical SMILES | C1=CC2=C(C=C1O)C(=CN2)CCN.Cl |
Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
