Anhydrochlortetracycline (hydrochloride)
Anhydrochlortetracycline was produced by the acid degradation of chlortetracycline. Anhydrochlortetracycline only have a fraction of the antibacterial activity of chlortetracycline. Anhydrochlortetracycline strongly inhibited the growth of Streptomyces aureofaciem. Anhydrochlortetracycline showed a rather specific activity against actinomycetes. Preliminary data indicated that the compound showed no obvious toxicity to mice at doses of 160 mg/kg. Anhydrochlortetracycline showed a substantial in vitro activity against N. asteroides and S. salmonicida pathogens of man and fish, respectively [1].
Reference:
[1] Goodman J J, Matrishin M, Backus E J. The effect of anhydrochlortetracycline on the growth of actinomycetes[J]. Journal of bacteriology, 1955, 69(1): 70.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 497.3 |
| Cas No. | 65490-24-6 |
| Formula | C22H21ClN2O7·HCl |
| Solubility | Soluble in DMSO |
| Chemical Name | (4S,4aS,12aS)-7-chloro-4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide, monohydrochloride |
| SDF | Download SDF |
| Canonical SMILES | OC1=C2C(O)=CC=C(Cl)C2=C(C)C3=C1C([C@@](C(C(C(N)=O)=C(O)[C@H]4N(C)C)=O)(O)[C@@]4([H])C3)=O.Cl |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
-
Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
- Datasheet
Chemical structure
