EB 47
Catalog No.
A4528
Potent PARP-1 inhibitor
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EB 47 is a potent inhibitor of PARP-1 with IC50 of 45 nM.
Physical Appearance | White solid |
Storage | Store at -20°C |
M.Wt | 610.45 |
Cas No. | 1190332-25-2 |
Formula | C24H27N9O6·2HCl |
Solubility | <30.52mg/ml in DMSO;insoluble in H2O |
Chemical Name | 2-(4-((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-carbonyl)piperazin-1-yl)-N-(1-oxoisoindolin-4-yl)acetamide dihydrochloride |
SDF | Download SDF |
Canonical SMILES | O[C@H]1[C@@H](O)[C@H](N(C=N2)C3=C2C(N)=NC=N3)O[C@@H]1C(N4CCN(CC(NC5=CC=CC6=C5CNC6=O)=O)CC4)=O.Cl.Cl |
Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
General tips | We do not recommend long-term storage for the solution, please use it up soon. |
EB 47 is a potent inhibitor of PARP1 with IC50 of 45 nM. | ||||||
Targets | PARP1 | |||||
IC50 | 45 nM |
Quality Control & MSDS
- View current batch:
-
Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
- Datasheet
Chemical structure
