NHS-SS-11-Biotin
Catalog No.
A8016
Amine-reactive biotinylation reagent, mid-length
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NHS-SS-11-biotin is a long-chain cleavable amine-reactive biotinylation reagent that has a spacer arm of 24.3 A in length due to the existence of a cross-bridge within its chemical structure. The long spacer arm creates an increased length between a covalently modified molecule and the bicyclic biotin rings that greatly enhances the ability of the molecule to bind to avidin or streptavidin probes. The NHS ester group of NHS-SS-11-biotin reacts with the amine groups of proteins and other molecule forming an amide bond and releasing of sulfo-NHS. NHS-SS-11-Biotin is a water-insoluble molecule that requires the dissolution of organic solvents prior to be added to aqueous reactions.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 575.72 |
| Cas No. | 142439-92-7 |
| Formula | C22H33N5O7S3 |
| Solubility | insoluble in H2O; insoluble in EtOH; ≥16.83 mg/mL in DMSO |
| Chemical Name | 2,5-dioxopyrrolidin-1-yl 3-((3-oxo-3-((2-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethyl)amino)propyl)disulfanyl)propanoate |
| SDF | Download SDF |
| Canonical SMILES | O=C1N[C@]2([H])[C@]([C@H](CCCCC(NCCNC(CCSSCCC(ON3C(CCC3=O)=O)=O)=O)=O)SC2)([H])N1 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
