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NHS-SS-11-Biotin

Catalog No.
A8016
Amine-reactive biotinylation reagent, mid-length
Grouped product items
SizePriceStock Qty
5mg
$45.00
In stock
10mg
$75.00
In stock
25mg
$150.00
In stock
50mg
$230.00
In stock
100mg
$350.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

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Background

NHS-SS-11-Biotin (CAS: 142439-92-7) is an amine-reactive biotinylation reagent commonly used in biochemical research. Structurally, it possesses an N-hydroxysuccinimide (NHS) ester group that covalently reacts with primary amines of target proteins or biomolecules, forming stable amide bonds and releasing sulfo-NHS. This reagent features a cleavable disulfide linker and an extended spacer arm of approximately 24.3 ?, enhancing probe accessibility to avidin or streptavidin conjugates. It is utilized extensively for reversible biotinylation, affinity purification, or labeling studies in proteomics and cell biology applications.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt575.72
Cas No.142439-92-7
FormulaC22H33N5O7S3
Solubilityinsoluble in H2O; insoluble in EtOH; ≥16.83 mg/mL in DMSO
Chemical Name2,5-dioxopyrrolidin-1-yl 3-((3-oxo-3-((2-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethyl)amino)propyl)disulfanyl)propanoate
SDFDownload SDF
Canonical SMILESO=C1N[C@]2([H])[C@]([C@H](CCCCC(NCCNC(CCSSCCC(ON3C(CCC3=O)=O)=O)=O)=O)SC2)([H])N1
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

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