NEO214
Catalog No.
BA3664
NEO214, an autophagy inhibitor, is a covalent coupling of a PDE4 inhibitor with perillyl alcohol with anticancer activity and blood-brain barrier (BBB) permeability.
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NEO214 is an autophagy inhibitor, a covalent coupling of a PDE4 inhibitor with perillyl alcohol, with anticancer activity and blood-brain barrier (BBB) permeability.NEO214 prevents autophagy-lysosomal fusion, which blocks autophagic flow and triggers cell death in glioma cells. The process involves activation, and (transcription factor EB) aggregation.NEO214 inhibits macroautophagy/autophagy in glioblastoma cells and has the potential to overcome chemoresistance in glioblastoma.
| Physical Appearance | An oil |
| Storage | -20°C |
| M.Wt | 453.57 |
| Cas No. | 1361198-80-2 |
| Formula | C27H35NO5 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |