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Moxalactam (sodium salt)

Catalog No.
C4121
β-lactam antibiotic
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
$50.00
In stock
250mg
$44.00
In stock
500mg
$67.00
In stock
1g
$112.00
In stock

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Email: [email protected]

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Background

Moxalactam (sodium salt) is a β-lactam antibiotic.

β-lactam antibiotics (beta-lactam antibiotics) are a class of broad-spectrum antibiotics that contain a beta-lactam ring in their molecular structures. Most β-lactam antibiotics act by inhibiting cell wall biosynthesis.

Moxalactam is an oxacephem antibiotic and inhibits most commonly occurring gram positive, gram negative, and anaerobic bacteria. Moxalactam was more active against Klebsiella and E coli than cefoperazone. Moxalactam did not inhibit methicillin-resistant S. aureus and Enterococci. Moxalactam had been extremely active against Haemophilis and Neisseria gonorrhoeae. Moxalactam was extremely resistant to hydrolysis by all plasmid and chromosmal β-lactamases [1]. In certain situations, Moxalactam impaired normal hemostasis and prolonged bleeding time [2].

References:
[1].  Neu HC. The in vitro activity, human pharmacology, and clinical effectiveness of new beta-lactam antibiotics. Annu Rev Pharmacol Toxicol. 1982;22:599-642.
[2].  Sattler FR, Weitekamp MR, Ballard JO. Potential for bleeding with the new beta-lactam antibiotics. Ann Intern Med. 1986 Dec;105(6):924-31.

Chemical Properties

StorageStore at -20°C
M.Wt564.4
Cas No.64953-12-4
FormulaC20H18N6O9S·2Na
SynonymsAntibiotic 6059S,Latamoxef,LY 127935
Solubility≥25.95mg/mL in DMSO
Chemical Name(6R,7R)-7-[[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, disodium salt
SDFDownload SDF
Canonical SMILESOC1=CC=C([[email protected]@H](C([O-])=O)C(N[[email protected]@]2(OC)[[email protected]](OCC(CSC3=NN=NN3C)=C4C([O-])=O)([H])N4C2=O)=O)C=C1.[Na+].[Na+]
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37°C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.

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