Losartan
Catalog No.
B1072
Angiotensin II receptor antagonist
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Losartan is an angiotensin II receptor antagonist, competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 422.91 |
| Cas No. | 114798-26-4 |
| Formula | C22H23ClN6O |
| Solubility | ≥2.48 mg/mL in H2O with gentle warming and ultrasonic; ≥2.9 mg/mL in EtOH with gentle warming; ≥84.6 mg/mL in DMSO |
| Chemical Name | [2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol |
| SDF | Download SDF |
| Canonical SMILES | CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)CO)Cl |
| Shipping Condition | Evaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request. |
| General tips | For obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months. |
Quality Control & MSDS
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Chemical structure
