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Catalog No.
Triazole antifungal agent
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
In stock
In stock
In stock
In stock

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Fluconazole is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.

Chemical Properties

StorageStore at -20°C
Cas No.86386-73-4
Solubilityinsoluble in H2O; ≥10.9 mg/mL in DMSO; ≥60.9 mg/mL in EtOH
Chemical Name2-(2,4-difluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)propan-2-ol
SDFDownload SDF
Canonical SMILESC1=CC(=C(C=C1F)F)C(CN2C=NC=N2)(CN3C=NC=N3)O
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.


Cell experiment [1]:

Cell lines

The Candida albicans reference strain SC5314

Preparation method

The solubility of this compound in DMSO is >10.9mg/mL. General tips for obtaining a higher concentration: Please warm the tube at 37℃ for 10 minutes and/or shake it in the ultrasonic bath for a while. Stock solution can be stored below -20℃ for several months.

Reacting condition

10 μg/ml; dissolved in Milli-Q water


In wild-type Candida albicans SC5314 cells, fluconazole (10 μg/ml) and doxycycline (50 μg/ml) inhibited cell growth in a dose dependent way.

Animal experiment [2]:

Animal models

C. albicans-infected p47phox-/- knockout mice

Dosage form

80 mg/kg/day for 13 days; diluted in saline; intraperitoneal injection


In C. albicans-infected p47phox-/- knockout mice, fluconazole significantly reduced splenic counts of C. albicans (P =0.008).

Other notes

Please test the solubility of all compounds indoor, and the actual solubility may slightly differ with the theoretical value. This is caused by an experimental system error and it is normal.


[1]. Alessandro Fiori and Patrick Van Dijck. Potent Synergistic Effect of Doxycycline with Fluconazole against Candida albicans Is Mediated by Interference with Iron Homeostasis. Antimicrob Agents Chemother. 2012 Jul; 56(7): 3785–3796.

[2]. Justina Y. Ju, Cynthia Polhamus, Kieren A. Marr, et al. Efficacies of Fluconazole, Caspofungin, and Amphotericin B in Candida glabrata-Infected p47phox-/- Knockout Mice. Antimicrob Agents Chemother. 2002 May; 46(5): 1240–1245.

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