Toggle Nav
  • Menu
  • Setting


Catalog No.
Anti-tuberculosis antibiotic
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
In stock
Ship with 10-15 days
Ship with 10-15 days

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors


Ethionamide is part of a group of drugs used in the treatment of drug resistant TB called thioamides. It is used as part of treatment regimens, generally involving 5 medicines, to treat MDR and XDR TB.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
Cas No.536-33-4
Solubility≥7.65 mg/mL in DMSO
Chemical Name2-ethylpyridine-4-carbothioamide
SDFDownload SDF
Canonical SMILESCCC1=NC=CC(=C1)C(=S)N
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.


Cell experiment [1]:

Cell lines

HepG2, Caco-2 and RAW macrophages

Preparation method

The solubility of this compound in DMSO is ≥7.65mg/mL. General tips for obtaining a higher concentration: Please warm the tube at 37 ℃ for 10 minutes and/or shake it in the ultrasonic bath for a while. Stock solution can be stored below -20℃ for several months.

Reacting condition

0.50 mM


In HepG2, Caco-2, and RAW macrophages, when Ethionamide concentration is higher than 0.50 mM, it is generally toxic to cells, but when Ethionamide is loaded into microparticles, the toxicity is significantly reduced. In the presence of thermal carbonized-porous silicon (TCPSi) particles, Ethionamide exhibits a rapid metabolic process.


[1]. Vale N, Mäkilä E, Salonen J, Gomes P, Hirvonen J, Santos HA. New times, new trends for ethionamide: In vitro evaluation of drug-loaded thermally carbonized porous silicon microparticles. Eur J Pharm Biopharm. 2012 Jun;81(2):314-23. doi: 10.1016/j.ejpb.2012.02.017. Epub 2012 Mar 6. PubMed PMID: 22418076.

Quality Control

Chemical structure