Toggle Nav
Close
  • Menu
  • Setting

Deacetylase Inhibitor Cocktail (100X in 70% DMSO)

Catalog No.
K1017
Deacetylase Inhibitor Cocktail
Grouped product items
SizePriceStock Qty
1ml
$50.00
In stock
10x1ml
$160.00
In stock
50x1ml
$640.00
In stock
100x1ml
$960.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Description

Deacetylase Inhibitor Cocktail (100× in 70% DMSO) is a reagent mixture designed to maintain protein acetylation states by targeting multiple classes of histone deacetylases (HDACs). It contains a combination of four compounds: Trichostatin A inhibiting class I/II HDACs; Sodium butyrate, functioning as a competitive inhibitor for the same HDAC classes; EX-527 specifically inhibiting SIRT1, with limited effects on SIRT2 and SIRT3; and Nicotinamide, acting as a broad inhibitor of Sirtuin enzymes. This cocktail is suited for cell biology and epigenetic studies where steady-state acetylation modifications are analyzed and offers researchers a useful approach to investigate chromatin remodeling, gene transcription regulation, DNA repair, signaling pathways, and cell-cycle dynamics.

Product Citation

Quality Control

Quality Control & MSDS

View current batch:
 

Protocol

Thaw on ice, add at 1:100 (v/v) dilution to solution samples (such as cell lysates or tissue extracts) before assaying.

Applications: WB, Co-IP, pull-down, IF, IHC, Flow Cytometry, kinase assay and etc.

Components and Storage

Catalog No. Product Name Summary Targets CAS Number Smiles
A8183 Trichostatin A (TSA) HDAC inhibitor DNA Damage/DNA Repair|HDAC 58880-19-6 CC(C=C(C)C=CC(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C
A4181 EX 527 (SEN0014196) SIRT1 inhibitor Chromatin/Epigenetics|Sirtuin 49843-98-3 C1CC(C2=C(C1)C3=C(N2)C=CC(=C3)Cl)C(=O)N
N1651 Nicotinamide PARP-1 inhibitor Natural Products 98-92-0 C1=CC(=CN=C1)C(=O)N
B1835 Sodium butyrate Histone deacetylase inhibitor 156-54-7 CCCC(=O)[O-].[Na+]
Store at -20°C, and stable for at least 12 months.

Storage

Store at -20°C, and stable for at least 12 months.