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Chidamide

Catalog No.
B5916
Novel HDAC inhibitor
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
$160.00
In stock
2mg
$88.00
In stock
5mg
$154.00
In stock
10mg
$264.00
In stock
50mg
$1,056.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

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Email: [email protected]

Worldwide Distributors

Background

Chidamide (CAS 743420-02-2) is a benzamide-based histone deacetylase (HDAC) inhibitor that targets enzymes responsible for the reversible acetylation of lysine residues on histone tails. By modulating HDAC activity, Chidamide promotes chromatin remodeling, influencing transcription factor access and subsequent gene transcription. In vitro studies on human leukemia cell lines and primary myeloid leukemia cells indicate that Chidamide induces cell cycle arrest at the G1 phase, differentiation, and apoptosis via ROS-dependent mechanisms. Therefore, Chidamide shows considerable potential in research focused on hematologic malignancies and cancer therapy.

Product Citation

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt390.41
Cas No.743420-02-2
FormulaC22H19FN4O2
Solubilityinsoluble in H2O; insoluble in EtOH; ≥18.55 mg/mL in DMSO
Chemical NameN-(2-amino-5-fluorophenyl)-4-((3-(pyridin-3-yl)acrylamido)methyl)benzamide
SDFDownload SDF
Canonical SMILESFC1=CC(NC(C2=CC=C(CNC(C=CC3=CC=CN=C3)=O)C=C2)=O)=C(N)C=C1
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Chemical structure

Chidamide

Related Biological Data

Chidamide

Related Biological Data

Chidamide