• We specialize in small molecule inhibitors, agonists, antagonists and screening libraries!
Search Site
Home >> Signaling Pathways >> Neuroscience >> Nicotinic Receptor >> Benzoquinonium dibromide
Related Products
Benzoquinonium dibromideinhibitor of AChR and ganglion

Benzoquinonium dibromide

Catalog No. B6297
Size Price Stock Qty
10mg $142.00 Ship Within 7 Days
50mg $600.00 Ship Within 7 Days

Tel: +1-832-696-8203

Email: sales@apexbt.com

Worldwide Distributors

Sample solution is provided at 25 µL, 10mM.

Quality Control

Quality Control & MSDS

View current batch:

Chemical structure

Benzoquinonium dibromide

Benzoquinonium dibromide Dilution Calculator

Concentration (start)
Volume (start)
Concentration (final)
Volume (final)


Benzoquinonium dibromide Molarity Calculator



Chemical Properties

Cas No. 311-09-1 SDF Download SDF
Chemical Name 3,3'-((3,6-dioxocyclohexa-1,4-diene-1,4-diyl)bis(azanediyl))bis(N-benzyl-N,N-diethylpropan-1-aminium) bromide
Canonical SMILES O=C1C(NCCC[N+](CC)(CC)CC2=CC=CC=C2)=CC(C(NCCC[N+](CC)(CC)CC3=CC=CC=C3)=C1)=O.[Br-].[Br-]
Formula C34H50Br2N4O2 M.Wt 706.6
Solubility Soluble in DMSO > 10 mM Storage Store at RT
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request


Benzoquinonium Dibromide (BZQ) is an inhibitor of acetylcholine receptor (AChR) and ganglion. BZQ activates nicotinic single channels but blocks open channels at the neuronal AChRs.
AChR is an integral membrane protein that responds to the binding of acetylcholine, a neurotransmitter. Nicotinic acetylcholine receptor (nAChR) are particularly responsive to nicotine and is a Na+ and K+ channel.
The effects of BZQ on α-BGT sensitive neuronal nAChRs were evaluated on outside-out patches excised from fetal rat hippocampal neurons cultured for 11 to 35 days and found that BZQ (0.1-10 μM) could activate single-channel currents. BZQ was also able to activate various channel conductance states. The two most frequently encountered conductance states activated by BZQ were 43 ± 3.3 pS and 30 ± 4.2 p5. In frog muscle fibers, BZQ is an open-channel blocker of the nAChR and also activates single-channel currents that are not blocked by a-BGT.
[1]. Pereira EF, Reinhardt-Maelicke S, Schrattenholz A, et al. Identification and functional characterization of a new agonist site on nicotinic acetylcholine receptors of cultured hippocampal neurons. J Pharmacol Exp Ther, 1993, 265(3): 1474-1491.