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BAFF, human recombinant protein

Catalog No.
BAFF, B cell activating factor, expressed in E.Coli.
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Human B cell activating factor (BAFF) is a 32 kDa transmembrane glycoprotein produced by T cells, macrophages, monocytes and dendritic cells. BAFF is a member of the TNF family of ligands and is involved in stimulation of B and T cell function. BAFF plays important roles in survival and maturation of peripheral B cells. BAFF signals through three different TNF receptors: TACI, BCMA and BAFF-R.

The human BAFF gene codes a 285 aa transmembrane protein containing a 46 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 218 amino acid extracellular domain. Recombinant human BAFF is a soluble protein containing 153 amino acid residues with a N-terminal His-tag (MW 19.335 kDa)

Biological Activity

Determined by the dose-dependent stimulation of IL-8 production by human PBMC.
ED50 < 10 ng/ml.          
Please note: results may vary with PBMC donors.

Quality Control

Quality Control & DataSheet

View current batch:
    Purity: ≥95%, by SDS-PAGE and HPLC.
    Endotoxin Level:< 0.1 ng/μg/span>

Related Biological Data



Gene ID: 10673 Accession #: Q9Y275
Alternate Names:human BAFF, h-BAFF, rh-BAFF, recombinant human BAFF, recombinant BAFF.
Source: Escherichia Coli. M.Wt: 19.335 kDa
Appearance: Lyophilized protein Storage: Store at -20°C
Formulation:Lyophilized from 0.3× PBS, pH 7.5.
Solubility:Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use.
Shipping Condition: Gel pack. Handling: Centrifuge the vial prior to opening.
Usage:For Research Use Only! Not to be used in humans.