β-Amyloid (1-16)
Catalog No.
C8646
β-Amyloid (1-16) is a metal-binding peptide fragment derived from β-amyloid, associated with Alzheimer's disease pathology.
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β-Amyloid (1-16) is an amyloidogenic peptide fragment derived from the N-terminal region of β-amyloid, a key protein involved in Alzheimer's disease (AD). This fragment retains the capacity to bind metal ions, implicating its role in metal ion homeostasis and aggregation processes. β-Amyloid peptides are known to form neurotoxic amyloid plaques in AD-affected brains, and the (1-16) region is critical in modulating interactions with metals such as copper and zinc, which are believed to influence peptide aggregation and neurotoxicity.
| Storage | Store at -20°C for 1 year. Powder: Store at -80°C for 2 years. |
| M.Wt | 1955.04 |
| Cas No. | 131580-10-4 |
| Formula | C84H119N27O28 |
| Synonyms | Amyloid β-Protein (1-16) |
| Solubility | Soluble in DMSO |
| Chemical Name | L-aspartyl-L-alanyl-L-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-aspartyl-L-serylglycyl-L-tyrosyl-L-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysine |
| SDF | Download SDF |
| Canonical SMILES | OC(C[C@H](N)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC2=CN=CN2)C(N[C@@H](CC(O)=O)C(N[C@@H](CO)C(NCC(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CC4=CN=CN4)C(N[C@@H](CC5=CN=CN5)C(N[C@@H] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |