Anti-CXCR4 Rabbit Polyclonal Antibody
Catalog No.
PA1109
Anti-CXCR4 Rabbit Polyclonal Antibody
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Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhance intracellular calcium ions and reduce cellular cAMP levels. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Could be involved in cerebellar development.
7852
CXCR4; C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; FB22; Fusin; HM89; LCR1; Leukocyte-derived seven transmembrane domain receptor; LESTR; NPYRL; Stromal cell-derived factor 1 receptor; SDF-1 receptor; CD antigen CD184
Rabbit
Human, Mouse
Unconjugated
Calculated MW: 40 kDa; Observed MW: 43 kDa
Unmodified
IgG
Polyclonal Antibody
Liquid
See label
Carrier Free
A synthesized peptide derived from human CXCR4
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IHC-P, ICC/IF
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.