Anti-ATM Rabbit Polyclonal Antibody
Catalog No.
PA1039
Anti-ATM Rabbit Polyclonal Antibody
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The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability.
472
ATM; Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 351 kDa; Observed MW: 351 kDa
Unmodified
IgG
Polyclonal Antibody
Liquid
See label
Carrier Free
A synthesized peptide derived from human ATM
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, ICC/IF, FC, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.