Anti-ATM Rabbit Monoclonal Antibody
Catalog No.
MA1352
Anti-ATM Rabbit Monoclonal Antibody
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The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability.
472
ATM; Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated
Rabbit
Human
Unconjugated
Calculated MW: 351 kDa; Observed MW: 351 kDa
Unmodified
IgG
Monoclonal Antibody
AP-17A12H11
Liquid
See label
Carrier Not Free
Recombinant protein of ATM
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.