Anti-Argonaute 2 Rabbit Monoclonal Antibody
Catalog No.
MA1299
Anti-Argonaute 2 Rabbit Monoclonal Antibody
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Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). Can also upregulate the translation of specific mRNAs under certain growth conditions. Binds to the AU element of the 3'-UTR of the TNF (TNF-alpha) mRNA and upregulates translation under conditions of serum starvation. Also required for transcriptional gene silencing (TGS), in which short RNAs known as antigene RNAs or agRNAs direct the transcriptional repression of complementary promoter regions.
27161
Ago 2; Argonaute 2; dAgo2; eIF2C 2; hAgo2; PPD
Rabbit
Human, Rat
Unconjugated
Calculated MW: 97 kDa; Observed MW: 97 kDa
Unmodified
IgG
Monoclonal Antibody
AP-20F12H12
Liquid
See label
Carrier Not Free
A synthetic peptide of human Argonaute-2
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.