Toggle Nav
Close
  • Menu
  • Setting

ANP (1-11), rat

Catalog No.
A1009
Vasodilator
Grouped product items
SizePriceStock Qty
1mg
$30.00
In stock
5mg
$90.00
In stock
10mg
$150.00
In stock
25mg
$210.00
In stock

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Atrial Natriuretic Peptide (ANP) (C49H84N20O15S) has the sequence of H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-OH, is a 28 amino acid peptide that is synthesized, stored, and released by atrial myocytes in response to atrial distension, angiotensin II stimulation, endothelin, and sympathetic stimulation. ANP is a powerful vasodilator, and a protein (polypeptide) hormone secreted by heart muscle cells. It is involved in the homeostatic control of body water, sodium, potassium and fat (adipose tissue). It is released by muscle cells in the upper chambers (atria) of the heart (atrial myocytes), in response to high blood pressure. ANP acts to reduce the water, sodium and adipose loads on the circulatory system, thereby reducing blood pressure.

A1009_1

Ref:

1. Widmaier, Eric P.; Hershel Raff, Kevin T. Strang (2008). Vander's Human Physiology, 11th Ed.. McGraw-Hill. pp. 291, 509–10.

2. Marieb Human Anatomy & Physiology 9th edition, chapter:16, page:629, question number:14

3. de Bold A (1985). "Atrial natriuretic factor: a hormone produced by the heart". Science 230 (4727): 767–70.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt1225.38
FormulaC49H84N20O15S
SynonymsH2N-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-OH
Solubility≥122.5 mg/mL in DMSO; insoluble in EtOH; ≥43.5 mg/mL in H2O
SDFDownload SDF
Canonical SMILESN[[email protected]@H](CO)C(N[[email protected]@H](CC(C)C)C(N[[email protected]@H](CCCNC(N)=N)C(N[[email protected]@H](CCCNC(N)=N)C(N[[email protected]@H](CO)C(N[[email protected]@H](CO)C(N[[email protected]@H](CS)C(N[[email protected]@H](CC1=CC=CC=C1)C(NCC(NCC(N[[email protected]@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.

Quality Control

Chemical structure

ANP (1-11), rat