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Adenosine-5'-diphosphate

Catalog No.
C4341
central component of energy storage, metabolism, and signal transduction in vivo;agonist of purinergic receptors
Grouped product items
SizePriceStock Qty
100mg
$55.00
In stock
250mg
$99.00
In stock
500mg
$176.00
In stock
1g
$297.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

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Background

Adenosine-5'-diphosphate (CAS 58-64-0), commonly known as ADP, is an endogenous nucleotide serving as an agonist of purinergic receptors. It activates various P2 receptor subtypes, exhibiting an IC50 of 67 nM at P2X2/3 receptors. ADP results from ATP hydrolysis mediated by ATPases and can be reconverted to ATP via ATP synthases or further processed to AMP and other metabolites. Through receptor modulation, ADP influences cellular functions including neural stem cell proliferation, vascular response, apoptosis, cytokine secretion, and kinase-driven phosphorylation pathways, thus playing a critical role in purinergic signaling research.

Chemical Properties

StorageStore at -20°C
M.Wt427.2
Cas No.58-64-0
FormulaC10H15N5O10P2
SynonymsAdenosine Pyrophosphate,ADP,5′-ADP
Solubility≥21.35 mg/mL in DMSO with gentle warming; insoluble in EtOH; ≥24.85 mg/mL in H2O
Chemical Nameadenosine 5'-(trihydrogen diphosphate)
SDFDownload SDF
Canonical SMILESO[C@H]1[C@H](N2C=NC3=C2N=CN=C3N)O[C@H](COP(OP(O)(O)=O)(O)=O)[C@H]1O
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

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