6-Bnz-cAMP sodium salt

6-Bnz-cAMP sodium salt (CAS 1135306-29-4) is a selective cAMP analogue that functions as an activator of protein kinase A (PKA)-dependent signaling pathways. It specifically targets the conserved cAMP-binding domains on PKA, triggering downstream phosphorylation events. Activation of PKA subsequently impacts signaling proteins such as CREB, whose phosphorylation state mediates processes like osteoblast differentiation. Experimental studies indicate 6-Bnz-cAMP promotes differentiation, mineralization, and early cell adhesion; notably, it drives osteogenic differentiation in MC3T3-E1 cells. Its potential for controlled release further suggests utility as a molecule for regenerative strategies in bone tissue engineering.