5-Formyl-dCTP
Catalog No.
B8117
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5-Formyl-dCTP is a modified cytosine-based deoxynucleoside triphosphate derivative capable of incorporation into DNA by DNA polymerase activity, resulting in the formation of 5-formylcytosine (5fC) modified bases. Presence of 5fC marks an intermediate step within active DNA demethylation pathways, impacting epigenetic regulatory processes and gene expression. It serves as a reagent in DNA modification and epigenomic studies, facilitating investigations into the functional roles of 5fC in replication fidelity, base excision repair mechanisms, transcriptional regulation, and chromatin remodeling dynamics.
| Physical Appearance | Solution |
| Storage | Store at -20°C or below |
| M.Wt | 495.1 |
| Formula | C10H16N3O14P3 (free acid) |
| Synonyms | 5-Formyl-2’-deoxycytidine-5’-Triphosphate, 5-fdCTP, 5-CHO-dCTP, 5-Fo-dCTP |
| Chemical Name | lithium (5-(4-amino-5-formyl-2-oxopyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl triphosphate |
| SDF | Download SDF |
| Canonical SMILES | NC(C(C([H])=O)=CN1C2CC(O)C(COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O)O2)=NC1=O.[Li+].[Li+].[Li+].[Li+] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
-
Purity = ≥90% by AX-HPLC
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
