DDR1/DDR2 receptors are unique receptor tyrosine kinases that bind to collagen and activated in several signaling pathways, including Shp-2, Src and MAPK. They have been associated with diseases like fibrosis, atherosclerosis and cancer.
- Cat.No. Product Name Information
- B3383 DDR1-IN-1 DDR1-IN-1 is a potent and selective DDR1 receptor tyrosine kinase inhibitor with IC50/EC50 of 105 nM/87 nM; 4-fold less potent for DDR2 (IC50= 413 nM).