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Broad Spectrum Protein Kinase Inhibitor

Broad spectrum protein kinase Inhibitor is a potent antineoplastic agent that blocks various protein kinase activities in cancer cells.

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  1. Cat.No. Product Name Information
  2. C4953 HA-100 (hydrochloride)
  3. C4439 PKR Inhibitor
  4. C4394 Rp-8-pCPT-Cyclic GMPS (sodium salt)
  5. C4363 Rp-8-bromo-Cyclic GMPS (sodium salt)
  6. B5001 H-9 dihydrochloride New Product
  7. B6342 H-7 dihydrochloride New Product
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  10. A8192 Staurosporine

    Staurosporine, an alkaloid produced in Streptomyces staurospores originally as an antifungal agent, is an inhibitor of a broad spectrum of protein kinases, including protein kinase C (PKC), Camp-dependent protein kinase (PKA), phosphorylase kinase, ribosomal protein S6 kinase, epidermal growth factor receptor (EGF-R) kinase and Ca2+/calmodulin-dependent protein kinase II (Ca/CaM PKII). The inhibition potency is strongest for PKC (IC50 = 2.7 nM) but several-fold lower for other protein kinases.

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