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Hedgehog

Hh (Hedgehog) signalling is a evolutionarily conserved pathway that is critical for embryonic development, tissue and organ morphogenesis. Mammalian Hh protein ligands include Sonic Hh, Desert Hh and Indian Hh. Dysfunctions of Hh singalling lead to developmental abnormalities and cancer.

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  1. Cat.No. Product Name Information
  2. B7669 20(S)-Hydroxycholesterol Allosteric activator of the Hedgehog signaling pathway Smoothened (Smo) oncoprotein
  3. A8658 AY 9944 dihydrochloride Hedgehog Inhibitor
  4. A8657 AZ 12080282 dihydrochloride Hedgehog inhibitor
  5. A8396 CHIR-99021 (CT99021) HCl GSK-3α/β inhibitor
  6. A8655 Ciliobrevin A Hh pathway antagonist
  7. C5138 CUR 61414 potent inhibitor of hedgehog-induced cellular activity
  8. A8340 Cyclopamine Hedgehog (Hh) signaling Inhibitor
  9. A3429 GANT 58 GLI antagonist,novel and potent
  10. A1615 GANT61 GLI antagonist
  11. A3021 GDC-0449 (Vismodegib) Hedgehog antagonist,potent and selective

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